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Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?

✍ Scribed by Bokoch, Gary M


Book ID
110015810
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
271 KB
Volume
5
Category
Article
ISSN
1350-9047

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✍ Wen-Hsiung Chan; Jau-Song Yu; Shiaw-Der Yang πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 364 KB πŸ‘ 2 views

Hyperosmotic shock elicits a stress response in mammalian cells and can lead to apoptotic cell death. In the present study, we report that hyperosmotic shock can induce activation of a 36 kDa kinase detected by an in-gel kinase assay in several cell types, including mouse Balb/c 3T3 fibroblasts, and