## Abstract A vast variety of naturally occurring substances have been shown to protect against experimental carcinogenesis and an increasing amount of evidence suggests that kaempferol may have cancer chemopreventative properties. However, the precise underlying protective mechanisms are poorly un
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Caspase- and p38-MAPK-dependent induction of apoptosis in A549 lung cancer cells by Newcastle disease virus
โ Scribed by Jianchun Bian; Kai Wang; Xiangang Kong; Huairan Liu; Fei Chen; Maozhi Hu; Xiaorong Zhang; Xinan Jiao; Baoxue Ge; Yantao Wu; Songshu Meng
- Publisher
- Springer Vienna
- Year
- 2011
- Tongue
- English
- Weight
- 624 KB
- Volume
- 156
- Category
- Article
- ISSN
- 1432-8798
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Human non-small cell lung cancer (NSCLC) cells were transfected with recombinant prodrug herpes simplex virus type I thymidine kinase (HSV-tk) cDNA, and the selected clones underwent apoptosis in response to induction by antiviral ganciclovir (GCV). The efficiency of GCV-induced growth inhibition an