𝔖 Bobbio Scriptorium
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Caspase activation and apoptosis in response to proteasome inhibitors

✍ Scribed by Henderson, C J; Aleo, E; Fontanini, A; Maestro, R; Paroni, G; Brancolini, C


Book ID
110017033
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
963 KB
Volume
12
Category
Article
ISSN
1350-9047

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## Abstract The proteasome is a multi‐subunit protease complex that is involved in intracellular protein degradation in eukaryotes. Previously, we have reported that selective, synthetic chymotryptic proteasome inhibitors inhibit A‐NK cell‐mediated cytotoxicity by approximately 50%; however, the ex