Caspase-3-like proteases and 6-hydroxydopamine induced neuronal cell death
โ Scribed by Richard C. Dodel; Yansheng Du; Kelly R. Bales; Zaodong Ling; Paul M. Carvey; Steven M. Paul
- Book ID
- 117387257
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 488 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0169-328X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Activation of proteolytic enzymes, including the caspase family of proteinases, is a feature characteristic of the apoptotic program. In the present study, we examined a potential role of intracellular proteinases in the death of neuronal PC12 and primary cultured rat microglial cells induced by 6-h
In this study, we examined the possibility that MPTP and 6-hydroxydopamine (6-OHDA) act on distinct cell death pathways in a murine dopaminergic neuronal cell line, MN9D. First, we found that cells treated with 6-OHDA accompanied ultrastructural changes typical of apoptosis, whereas MPP ุ treatment