Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death

c-Rel is crucial for the induction of Fo

c-Rel is crucial for the induction of Foxp3+ regulatory CD4+ T cells but not TH17 cells

✍ Alexander Visekruna; Magdalena Huber; Anne Hellhund; Evita Bothur; Katharina Rei 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 1 views

## Abstract The NF‐κB/Rel family member c‐Rel was described to be required for the development of T~H~1 responses. However, the role of c‐Rel in the differentiation of T~H~17 and regulatory CD4^+^Foxp3^+^ T cells (Treg) remains obscure. Here, we show that in the absence of c‐Rel, __in vitro__ diffe