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Caspase-3 cleavage and nuclear localization of caspase-activated DNase in human temporal lobe epilepsy

✍ Scribed by Schindler, Clara K; Pearson, Erik G; Bonner, Helena P; So, Norman K; Simon, Roger P; Prehn, Jochen H M; Henshall, David C

Book ID
110046591
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
227 KB
Volume
26
Category
Article
ISSN
0271-678X

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## Abstract In a study examining for apoptosis in spontaneously hypertensive rats (SHR), we observed the constitutive presence of activated caspase 3 in Bergmann glia. We then examined stroke‐prone SHR as well as the normotensive strains Wistar, Wistar Kyoto, and Sprague‐Dawley. In all these strain