Case–control study on the therapy of childhood cancer and the occurrence of second malignant neoplasms in Germany
✍ Scribed by Peter Kaatsch; Irene Reinisch; Claudia Spix; Frank Berthold; Gritta Janka-Schaub; Andreas Mergenthaler; Jörg Michaelis; Maria Blettner
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 226 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0957-5243
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## Abstract Radiotherapy and chemotherapy are associated with an increased risk of a second malignant neoplasm (SMN) after a cancer during childhood. This study specified the dose‐effect relationship between radiotherapy, chemotherapy and the risk of a SMN, and investigated the effect of chemo‐radi
## Abstract To evaluate the incidence of second malignant tumors in a cohort of subjects previously treated for childhood cancer, we analyzed data from the Off‐Therapy Registry (OTR) of the Italian Association of Pediatric Hematology/Oncology, which collects information on children treated for Hodg