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Case report: Neuroleptic malignant syndrome in an elderly patient: Problems in management

✍ Scribed by Dr. Adityanjee; S. K. Jayaswal; S. P. Chan; M. Subramaniam

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
339 KB
Volume
7
Category
Article
ISSN
0885-6230

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✦ Synopsis

Abstract

An elderly patient with probable dementing illness was treated with haloperidol and trifluoperazine for control of agitation. The patient developed neuroleptic malignant syndrome characterized by cogwheel rigidity, deterioration in sensorium, hyperpyrexia, mutism, autonomic dysfunction, elevated leucocyte count and serum creatinine phosphokinase. After an initial diagnostic delay treatment with very low doses of bromocriptine resulted in hypotension followed by acute renal failure and death. Problems in the management of NMS in elderly patients with concurrent psychiatric illness and/or dementing illness are discussed.

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