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Case report: Interleukin-6 positive follicular hyperplasia in the lymph node of a patient with rheumatoid arthritis

✍ Scribed by Yukiko Numata; Yasushi Matsuura; Saburo Onishi; Yasutake Yamamoto; Fumitoshi Ohno; Hiromi Tagoh; Kazuyuki Yoshizaki; Shigeyoshi Fujimoto; Hiroshi Yamamoto

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
292 KB
Volume
36
Category
Article
ISSN
0361-8609

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✦ Synopsis

We examined interleukin-6 production in the hyperplastic lymph node of a 77-year-old male rheumatoid arthritis patient with lymphadenopathy. The interleukin-6 production of the lymph node was observed by both immunohistological staining and in vitro culture. The results suggest that interleukin-6 plays a significant pathogenic role in the etiology of the lymphadenopathy seen in many rheumatoid arthritis patients.

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