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Case report: Hepatitis A preceding Guillain–Barré Syndrome

✍ Scribed by Shobha D. Chitambar; Rahul S. Fadnis; Madhuri S. Joshi; A. Habbu; S.G. Bhatia


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
92 KB
Volume
78
Category
Article
ISSN
0146-6615

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✦ Synopsis


A case of acute hepatitis A with Guillain-Barré Syndrome subtype AMAN (acute motor axonal neuropathy) in a 17-year-old male is reported. Serum and cerebrospinal fluid were positive for anti-hepatitis A virus (HAV) IgM, IgG, and IgA. The onset of the syndrome was evident in week 3 of illness. The remarkably high titers of serum anti-HAV IgG appeared unique to a hepatitis A patient with the syndrome. Phylogenetic analysis of the HAV genome detected in the serum and feces revealed genotype IIIA, circulating commonly in Pune, western India.


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