A 57-year-old woman developed rapidly progressive, symmetric, extremity weakness, facial diplegia, ophthalmoplegia, respiratory insufficiency, and sensory ataxia over a 3-week period. Electrodiagnostic studies were performed on days 6, 13, and 50 following the onset of weakness. Motor nerve conducti
Case report: Hepatitis A preceding Guillain–Barré Syndrome
✍ Scribed by Shobha D. Chitambar; Rahul S. Fadnis; Madhuri S. Joshi; A. Habbu; S.G. Bhatia
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 92 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0146-6615
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✦ Synopsis
A case of acute hepatitis A with Guillain-Barré Syndrome subtype AMAN (acute motor axonal neuropathy) in a 17-year-old male is reported. Serum and cerebrospinal fluid were positive for anti-hepatitis A virus (HAV) IgM, IgG, and IgA. The onset of the syndrome was evident in week 3 of illness. The remarkably high titers of serum anti-HAV IgG appeared unique to a hepatitis A patient with the syndrome. Phylogenetic analysis of the HAV genome detected in the serum and feces revealed genotype IIIA, circulating commonly in Pune, western India.
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