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Case Report: Determination of Primary Foci of Metastatic Tumors by p53 Mutational Analysis in Intraesophageal Multiple Carcinomas

โœ Scribed by Shirou Kuwabara; Tadashi Nishimaki; Yoichi Ajioka; Shintarou Komukai; Tsutomu Suzuki; Hidenobu Watanabe; Katsuyoshi Hatakeyama


Book ID
110377414
Publisher
Springer US
Year
1998
Tongue
English
Weight
71 KB
Volume
43
Category
Article
ISSN
0163-2116

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## Abstract We studied the frequency and pattern of __p53__ mutations in 16 mouse skin primary squamous carcinomas induced by chemical carcinogens and their 19 matched metastases. The molecular changes were analyzed by polymerase chain reactionโ€singleโ€strand conformation polymorphism and subsequent