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Case-Control Association Testing with Related Individuals: A More Powerful Quasi-Likelihood Score Test

✍ Scribed by Timothy Thornton; Mary Sara McPeek


Book ID
117855229
Publisher
American Society of Human Genetics
Year
2007
Tongue
English
Weight
310 KB
Volume
81
Category
Article
ISSN
0002-9297

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## Abstract In case‐control single nucleotide polymorphism (SNP) data, the allele frequency, Hardy Weinberg Disequilibrium, and linkage disequilibrium (LD) contrast tests are three distinct sources of information about genetic association. While all three tests are typically developed in a retrospe