Cascade Alkenyl Amination/Heck Reaction Promoted by a Bifunctional Palladium Catalyst: A Novel One-Pot Synthesis of Indoles from o-Haloanilines and Alkenyl Halides.

Cascade Alkenyl Amination/Heck Reaction

Cascade Alkenyl Amination/Heck Reaction Promoted by a Bifunctional Palladium Catalyst: A Novel One-Pot Synthesis of Indoles from o-Haloanilines and Alkenyl Halides

✍ José Barluenga; M. Alejandro Fernández; Fernando Aznar; Carlos Valdés 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 1 views

## Abstract A novel approach for the synthesis of the important indole ring is described. Indoles are obtained from __o__‐bromoanilines and alkenyl halides in a Pd‐catalyzed cascade process that involves an alkenyl amination followed by an intramolecular Heck reaction. The overall process represent