Cartilage destruction and osteophytes in instability-induced murine osteoarthritis: Role of TGFβ in osteophyte formation?
✍ Scribed by Wim B. van den Berg; Gerjo J. V. M. van Osch; Peter M. van der Kraan; Henk M. van Beuningen
- Book ID
- 105426793
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1993
- Tongue
- English
- Weight
- 825 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objective Osteoarthritis (OA) is characterized by cartilage damage, synovial fibrosis, and osteophyte formation. Both transforming growth factor β (TGFβ) and bone morphogenetic protein 2 (BMP‐2) can induce the formation of osteophytes during OA, but their specific role in this proce
## Objective: It has been suggested that subchondral bone remodeling plays a role in the progression of osteoarthritis (oa). to test this hypothesis, we characterized the changes in the rat anterior cruciate ligament transection (aclt) model of oa and evaluated the effects of alendronate (aln), a p