๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Cartilage cell clusters

โœ Scribed by Martin K. Lotz; Shuhei Otsuki; Shawn P. Grogan; Robert Sah; Robert Terkeltaub; Darryl D'Lima


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
717 KB
Volume
62
Category
Article
ISSN
0004-3591

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๐Ÿ“œ SIMILAR VOLUMES


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## Abstract Traumatic articular cartilage injuries heal poorly and may predispose patients to the early onset of osteoarthritis. One current treatment relies on surgical delivery of autologous chondrocytes that are prepared, prior to implantation, through ex vivo cell expansion of cartilage biopsy

Clonal growth of differentiated rabbit c
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Single cell suspensions have been prepared from rabbit cartilage by collagenase digestion in the presence of fetal bovine serum. When inoculated into medium F12 supplemented with 5% fetal bovine serum and 5% rabbit serum, the cartilage cell suspensions yield large healthy colonies of epithelial-like

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## Abstract The longitudinal growth of endochondral bones is governed by proliferation and hypertrophic differentiation of growth plate chondrocytes. Numerous growth factors and hormones have been implicated in the regulation of these processes, but the intracellular mechanisms involved remain much