Cartilage and Osteoarthritis Volume 100 || Culture of Chondrocytes in Alginate Beads
✍ Scribed by Sabatini, Massimo; Pastoureau, Philippe; De Ceuninck, Fr�d�ric
- Book ID
- 120084746
- Publisher
- Humana Press
- Year
- 2004
- Weight
- 443 KB
- Category
- Article
- ISBN-13
- 9781592598106
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The purpose of this study was to investigate the influence of hydrostatic pressure (HP) on apoptosis and expression of heat-shock protein 70 (HSP70) in chondrocytes cultured in alginate beads. Chondrocytes were isolated from the articular cartilage of rabbit joints and seeded in alginate beads. The
Chondrocytes from 21-day-old rat fetal nasal cartilage were cultured in alginate beads for up to 20 days. It was found that chondrocytes retained their spherical shape and typical chondrocytic appearance. During the culture time, chondrocytes underwent differentiation, as demonstrated by the alkalin