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Carteraol E, a potent polyhydroxyl ichthyotoxin from the dinoflagellate Amphidinium carterae
β Scribed by Shin-Jong Huang; Chih-Ming Kuo; Ying-Chih Lin; Yi-Min Chen; Chung-Kuang Lu
- Book ID
- 104096428
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 390 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Carteraol E (1), C 74 H 126 O 24 , a polyhydroxyl ichthyotoxin, was isolated from the lab-cultured marine dinoflagellate Amphidinium carterae. Carteraol E possessed three tetrahydropyrans, and 19 hydroxyl groups on a C69-linear aliphatic chain with a ketone moiety, an exo-methylene, and three methyl branches. The structure was elucidated by extensive analyses of 2D NMR spectra. Cateraol E exhibited potent ichthyotoxicity with LD 50 value of 0.28 lM, and antifungal activity against Aspergillus niger.
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