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CART protects brain from damage through ERK activation in ischemic stroke

✍ Scribed by Jia Jia; Xuemei Chen; Wenjing Zhu; Yun Luo; Zichun Hua; Yun Xu

Book ID
113824527
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
462 KB
Volume
42
Category
Article
ISSN
0143-4179

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## Abstract The mechanism by which MCI‐186 (3‐methyl‐1‐phenyl‐2‐prazolin‐5‐one) exerts protective effects during cerebral infarction, other than its function as a radical scavenger, has not been fully elucidated. Here, we found that MCI‐186 stimulates intracellular survival signaling in vivo and in