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Carrier-mediated transport of vasorpressin across the blood-brain barrier of the mouse

✍ Scribed by Dr. W. A. Banks; A. J. Kastin; A. Horvath; E. A. Michals

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
708 KB
Volume
18
Category
Article
ISSN
0360-4012

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✦ Synopsis

A brain to blood carrier-mediated transport system observation that many of the central effects observed with for arginine vasopressin (AVP) was investigated in the intraventricular administration of AVP can also be mice after intraventricular injection of iodinated AVP achieved by injection of substantially larger amounts peand varying amounts of unlabeled material or candiripherally. In addition, CSF levels of AVP tend to corredate inhibitors. Residual activity in the brain detected late with plasma levels [Leurssen and Robertson, 1980; after decapitation was used as the main determinant Hammer et al, 1982; Simon-Oppermann, 1983; Szczeof transport activity. The half-time disappearance of panska-Sadowska et al, 19831 and many, but not all, iodinated AVP from the brain was 12.4 min, the V,,, treatments that increase plasma levels may also increase was 1.41 nmol/g-min, and the apparent K, was 28.7 CSF levels [

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