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Carrier-Mediated Transport of Macrolide Antimicrobial Agents Across Caco-2 Cell Monolayers

✍ Scribed by Hidetaka Saito; Yoshiki Fukasawa; Yoko Otsubo; Kenji Yamada; Hitoshi Sezaki; Shinji Yamashita

Book ID
110251450
Publisher
Springer US
Year
2000
Tongue
English
Weight
596 KB
Volume
17
Category
Article
ISSN
0724-8741

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✍ Han-Joo Maeng; Ho-Jung Yoo; In-Wha Kim; Im-Sook Song; Suk-Jae Chung; Chang-Koo S πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 116 KB

The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras