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Carotid intima-media thickness in Parkinson's disease

โœ Scribed by Jong-Moon Lee; Kun-Woo Park; Woo-Keun Seo; Moon Ho Park; Changsu Han; Inho Jo; Sangmee Ahn Jo

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
62 KB
Volume
22
Category
Article
ISSN
0885-3185

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โœฆ Synopsis

Abstract

There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intimaโ€media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ยฑ 0.179 mm vs. 0.913 ยฑ 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis. ยฉ 2007 Movement Disorder Society

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