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Carnosine pretreatment protects against hypoxia–ischemia brain damage in the neonatal rat model

✍ Scribed by Xiangmin Zhang; Lili Song; Xiuyong Cheng; Yi Yang; Bin Luan; Liting Jia; Falin Xu; Zhan Zhang

Book ID: 113589401
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 488 KB
Volume: 667
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2011.06.003

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## Abstract Developing oligodendrocytes (pre‐OLs) are highly vulnerable to hypoxic‐ischemic injury and associated excitotoxicity and oxidative stress. 17β‐Estradiol plays an important role in the development and function of the CNS and is neuroprotective. The sudden drop in circulating estrogen aft