Betulinic acid suppresses constitutive a
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Thangaiyan Rabi; Sanjeev Shukla; Sanjay Gupta
📂
Article
📅
2008
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John Wiley and Sons
🌐
English
⚖ 251 KB
## Abstract Development of chemoresistance in androgen‐refractory prostate cancer cells is partly due to constitutive activation of Rel/NF‐κB transcription factors that regulate several cell survival and anti‐apoptotic genes. In this study we examined whether betulinic acid (BetA), a pentacyclic tr