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Carnitine insufficiency during cyclophosphamide and ifosfamide-induced cardiomyopathy

✍ Scribed by Sayed-Ahmed, M.M.; Aldelemy, M.L.; Hafez, M.M.; Al-Shabanah, O.A.

Book ID: 125822655
Publisher: Elsevier
Year: 2014
Tongue: English
Weight: 174 KB
Volume: 2
Category: Article
ISSN: 2213-4344
DOI: 10.1016/j.phanu.2013.11.015

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Fatal cardiomyopathy developed in two patients receiving cyclophosphamide in preparation for bone marrow transplantation. Both patients had normal EKGs prior to receiving cyclophosphamide in total doses of 168 mg/kg (case 1) and 144 mgkg (case 2) and subsequently developed loss of voltage and ST-T w