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CARNITINE DEFICIENCY: A POSSIBLE MECHANISM FOR VALPROATE HEPATOTOXICITY

✍ Scribed by Coulter, DavidL.


Book ID
122762862
Publisher
The Lancet
Year
1984
Tongue
English
Weight
171 KB
Volume
323
Category
Article
ISSN
0140-6736

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The authors analyzed the association of L-carnitine treatment with hepatic survival in 92 patients with severe, symptomatic, valproate-induced hepatotoxicity. Forty-eight percent of the 42 patients treated with L-carnitine survived, but only 10% of the 50 patients treated solely with aggressive supp