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Carney complex: In a patient with multiple blue naevi and lentigines, suspect cardiac myxoma

✍ Scribed by Narelle R Bleasel; Karen M Stapleton


Book ID
104468943
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
48 KB
Volume
40
Category
Article
ISSN
0004-8380

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✦ Synopsis


Carney complex is characterized by spotty pigmentation (blue naevi and lentigines), myxomas (cardiac, cutaneous, mammary), endocrine over‐activity (Cushing’s syndrome, acromegaly), testicular tumours, and schwannomas. We report a male with multiple blue naevi, lentigines, testicular large cell calcifying Sertoli‐cell tumour and four cardiac myxomas. The myxomas caused two cerebrovascular accidents and a myocardial infarction. All patients with multiple blue naevi or lentigines should be investigated for the life‐threatening association of cardiac myxomas.


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## Summary Carney complex is a rare cardiocutaneous syndrome with an autosomal‐dominant inheritance pattern. Apart from its cutaneous manifestations of multiple blue naevi and lentigines, it can involve multiple other organ systems, particularly the heart, where myxoma tumours commonly develop and