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CARM1 but not Its Enzymatic Activity Is Required for Transcriptional Coactivation of NF-κB-Dependent Gene Expression

✍ Scribed by Sandrine Jayne; Karin M. Rothgiesser; Michael O. Hottiger


Book ID
116664289
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
886 KB
Volume
394
Category
Article
ISSN
0022-2836

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## Abstract In response to inflammation stimuli, tumor necrosis factor‐α (TNF‐α) induces expression of cell adhesion molecules (CAMs) in endothelial cells (ECs). Studies have suggested that the nuclear factor‐κB (NF‐κB) and the p38 MAP kinase (p38) signaling pathways play central roles in this proc