## Abstract In this study, specific binding sites for [^3^H]‐LTC~4~ on membrane preparations from American bullfrog (__Rana catesbeiana__) brain were characterized. Binding assays were done in the presence of serine (5mM) borate (10 mM) for 30 min at 23°C. Under these conditions, no metabolism of L
Cardiovascular responses to catecholamines at 12°C in the American bullfrog (Rana catesbeiana)
✍ Scribed by Herman, Ceil A. ;Robleto, Daniel O. ;Mata, Paula L. ;Heller, R. Scott
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 571 KB
- Volume
- 240
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
✦ Synopsis
The effects of epinephrine, norepinephrine, phenylephrine, and isoproterenol on blood pressure and heart rate were studied in cannulated American bullfrogs, Rana catesbeiana. The bullfrogs were chronically cannulated with a T cannula in the right sciatic artery. In warm-acclimated (22°C) bullfrogs, preinjection mean systemic arterial pressure (SAP) prior to experimental treatment was 13.1 &-0.7 mm Hg. Reinjection heart rate was 34.8 rf: 1.8 beats per minute. These parameters were lower in cold-acclimated (12°C) bullfrogs. Cold-acclimated animals had mean SAP values of 8.2 0.3 mm Hg, and heart rate was 11.1 rt 1.1 beats per minute. Epinephrine, norepinephrine,
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