Cardiovascular magnetic resonance myocardial feature tracking detects quantitative wall motion during dobutamine stress

✍ Scribed by Andreas Schuster; Shelby Kutty; Asif Padiyath; Victoria Parish; Paul Gribben; David A Danford; Marcus R Makowski; Boris Bigalke; Philipp Beerbaum; Eike Nagel

• Book ID: 104498519
• Publisher: BioMed Central
• Year: 2011
• Tongue: English
• Weight: 388 KB
• Volume: 13
• Category: Article
• ISSN: 1097-6647
• DOI: 10.1186/1532-429x-13-58

✦ Synopsis

Background: Dobutamine stress cardiovascular magnetic resonance (DS-CMR) is an established tool to assess hibernating myocardium and ischemia. Analysis is typically based on visual assessment with considerable operator dependency. CMR myocardial feature tracking (CMR-FT) is a recently introduced technique for tissue voxel motion tracking on standard steady-state free precession (SSFP) images to derive circumferential and radial myocardial mechanics. We sought to determine the feasibility and reproducibility of CMR-FT for quantitative wall motion assessment during intermediate dose DS-CMR.

Methods: 10 healthy subjects were studied at 1.5 Tesla. Myocardial strain parameters were derived from SSFP cine images using dedicated CMR-FT software (Diogenes MRI prototype; Tomtec; Germany). Right ventricular (RV) and left ventricular (LV) longitudinal strain (Ell RV and Ell LV ) and LV long-axis radial strain (Err LAX ) were derived from a 4chamber view at rest. LV short-axis circumferential strain (Ecc SAX ) and Err SAX ; LV ejection fraction (EF) and volumes were analyzed at rest and during dobutamine stress (10 and 20 μg • kg -1 • min -1 ).

Results: In all volunteers strain parameters could be derived from the SSFP images at rest and stress. Ecc SAX values showed significantly increased contraction with DSMR (rest: -24.1