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Cardiovascular effects of two new calcium antagonists, PY 108-068 and PN 200-110, in conscious spontaneously hypertensive rats

✍ Scribed by Christian Barrès; Catherine Cerutti; Benoît Morin; Jean Sassard

Book ID: 117958756
Publisher: Nature Publishing Group
Year: 1988
Tongue: English
Weight: 915 KB
Volume: 93
Category: Article
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1988.tb11419.x

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## Abstract Benidipine hydrochloride is a calcium antagonist with a 1,4‐dihydropyridine derivative structure, and exhibits long‐lasting antihypertensive effects by inhibiting the voltagedependent Ca^2+^ channels. This study was undertaken to examine the effect of benidipine on central haemodynamics