Common colorectal cancer risk variants i
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Michael N. Passarelli; Anna E. Coghill; Carolyn M. Hutter; Yingye Zheng; Karen W
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Article
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2011
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John Wiley and Sons
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English
β 555 KB
## Abstract Common single nucleotide polymorphisms (SNPs) in __SMAD7__ (18q21) have been linked to colorectal cancer (CRC) risk in genomeβwide association studies, but little is known about their effects on survival. SMAD7 regulates gastrointestinal inflammation by inhibiting transforming growth fa