Gene therapy with adenovirus-delivered i
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Diana Vavrincova-Yaghi; Leo E. Deelman; Harry van Goor; Marc Seelen; Ido P. Kema
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Article
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2011
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John Wiley and Sons
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English
⚖ 285 KB
## Abstract ## Background Indoleamine 2,3‐dioxygenase (IDO), the rate‐limiting enzyme in the tryptophan catabolism, has recently emerged as an important immunosuppressive enzyme involved in the regulation of both physiologic (maternal tolerance), as well as pathologic (neoplasia, autoimmune diseas