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Cardiotrophin-1, a novel cytokine that induces cardiac myocyte hypertrophy

โœ Scribed by Diane Pennica; Kathleen L. King; Kenneth R. Chien; Joffre B. Baker; William I. Wood


Book ID
116172715
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
164 KB
Volume
6
Category
Article
ISSN
1043-4666

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## Abstract Cellular mechanisms causing cardiac hypertrophy are currently under intense investigation. We report a novel finding in the TGFฮฒ inducible early gene (TIEG) null mouse implicating TIEG1 in cardiac hypertrophy. The TIEG^โˆ’/โˆ’^ knockโ€out mouse was studied. Male mice age 4โ€“16 months were cha