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Cardiotoxic potential and CNS effects of first-generation antihistamines

✍ Scribed by Maurizio Taglialatela; Henk Timmerman; Lucio Annunziato

Book ID
117341971
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
410 KB
Volume
21
Category
Article
ISSN
0165-6147

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## Background: The first generation antihistamines, such as diphenhydramine, are fairly potent muscarinic antagonists in addition to being h1 selective antihistamines. the antimuscarinic action is often not desirable since it is in part responsible for the drying of secretions in the airways and th