Cardiosulfa, a Small Molecule that Induces Abnormal Heart Development in Zebrafish, and Its Biological Implications

✍ Scribed by Sung-Kyun Ko; Hui Juan Jin; Da-Woon Jung; Xizhe Tian; Injae Shin

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 669 KB
• Volume: 48
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200902370

✦ Synopsis

Cardiosulfa, a Small Molecule that Induces Abnormal Heart Development in Zebrafish, and Its Biological Implications** Scheme 1. a) Preparation of a sulfonamide library by using solutionphase chemistry (substituents R 1 , R 2 , and R 3 are given in the Supporting Information, Scheme S1). b) Structure of cardiosulfa.

[*] S.