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Cardiopulmonary fitness and muscle strength in patients with osteogenesis imperfecta type I

✍ Scribed by Tim Takken; Heike C. Terlingen; Paul J.M. Helders; Hans Pruijs; Cornelis K. van Der Ent; Raoul H.H. Engelbert


Book ID
116682952
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
190 KB
Volume
145
Category
Article
ISSN
1097-6833

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## Communicated by Richard G.H. Cotton Mutations in the type I collagen genes COL1A1 and COL1A2 are responsible for the dominantly inherited connective tissue disorder osteogenesis imperfecta (OI). The severity of OI is diverse, ranging from perinatal lethality to a very mild phenotype that is cha