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Cardioprotective activity of dehydrosilybin is linked to its uncoupler-like behavior

✍ Scribed by Eva Gabrielova; Jitka Vostalova; Vladimir Kren; Radek Gazak; Martin Jaburek; Martin Modriansky


Book ID
113484795
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
58 KB
Volume
1797
Category
Article
ISSN
0005-2728

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## Abstract Tryptophan hydroxylase‐2 (TPH2) is the rate‐limiting enzyme of brain serotonin synthesis. The C1473G polymorphism in the mouse tryptophan hydroxylase‐2 gene affects the enzyme's activity. In the present study, we investigated the linkage between the C1473G polymorphism, enzyme activity