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Cardiomyopathies and mitochondrial DNA mutations

โœ Scribed by Nobuakira Takeda


Book ID
110242401
Publisher
Springer
Year
1997
Tongue
English
Weight
46 KB
Volume
176
Category
Article
ISSN
0300-8177

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Mutations occur in mitochondrial DNA (mtDNA) in a strand-asymmetric manner. The suppressed usage of cysteine residues in the H-strandencoded subunits can be ascribed to the mutational instability of the codon for cysteine. The usage of cysteine was suppressed even in the L-strand-encoded ND6 subunit