Cardiac sympathetic denervation preceding motor signs in Parkinson disease
β Scribed by David S. Goldstein; Yehonatan Sharabi; Barbara I. Karp; Oladi Bentho; Ahmed Saleem; Karel Pacak; Graeme Eisenhofer
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 213 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0959-9851
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## Abstract [^123^I]Metaiodobenzylguanidine ([^123^I]MIBG) cardiac scintigraphy could be helpful to differentiate Parkinson's disease (PD) from multiple system atrophy (MSA), demonstrating that, in PD with autonomic failure but not in MSA, there is a myocardial postganglionic sympathetic dysfunctio
## Abstract Attention has been drawn to cardiac sympathetic denervation in Parkinson's disease (PD) based on clinical studies using [123I] metaiodobenzylguanidine scintigraphy; however, the histologic correlates and time course of cardiac sympathetic denervation are poorly understood. To address th
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