โ Scribed by Masaki Ieda, Wolfram-Hubertus Zimmermann (eds.)
No coin nor oath required. For personal study only.
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair.
Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged.
The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Front Matter ....Pages i-vii
Past and Future of Cell-Based Heart Repair (Ahmed I. Mahmoud, Richard T. Lee)....Pages 1-17
Progenitor Cells from the Adult Heart (Georgina M. Ellison-Hughes, Fiona C. Lewis)....Pages 19-39
Epicardial Progenitors in the Embryonic and Adult Heart (Cristina Villa del Campo, Joaquim Miguel Vieira, Paul R. Riley)....Pages 41-65
Generation and Application of Human Pluripotent Stem Cell-Derived Cardiomyocytes (Adam J. T. Schuldt, Marisol Romero-Tejeda, Paul W. Burridge)....Pages 67-106
Differentiation and Use of Induced Pluripotent Stem Cells for Cardiovascular Therapy and Tissue Engineering (Saidulu Mattapally, W. Kevin Cukier-Meisner, Jianyi Zhang)....Pages 107-122
Direct Cardiac Reprogramming (Sho Haginiwa, Masaki Ieda)....Pages 123-143
Application of the Suspension Culture System for Scale-Up Manufacture of hPSCs and hPSC-Derived Cardiomyocytes (Vincent C. Chen, Larry A. Couture, Joseph Gold)....Pages 145-161
Purification of Pluripotent Stem Cell-Derived Cardiomyocytes for Safe Cardiac Regeneration (Shugo Tohyama, Keiichi Fukuda)....Pages 163-176
State of the Art in Cardiomyocyte Transplantation (Matthew E. Hartman, James J. H. Chong, Michael A. Laflamme)....Pages 177-218
State-of-the-Art in Tissue-Engineered Heart Repair (Buntaro Fujita, Malte Tiburcy, Stephan Ensminger, Wolfram-Hubertus Zimmermann)....Pages 219-239
Imaging Cardiac Stem Cell Therapy (Xulei Qin, Ian Y. Chen, Joseph C. Wu)....Pages 241-258
Stem Cell Transplant Immunology (Katharine K. Miller, Sonja Schrepfer)....Pages 259-274
Human Physiology
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