Cardiac biopsy in skeletal myopathy: Report of a case with myocardial mitochondrial abnormalities

✍ Scribed by E. H. Mackay; R. S. Brown; D. Pickering

• Publisher: John Wiley and Sons
• Year: 1976
• Tongue: English
• Weight: 990 KB
• Volume: 120
• Category: Article
• ISSN: 0022-3417
• DOI: 10.1002/path.1711200105

✦ Synopsis

Transvenous right ventricular endomyocardial biopsy in an 11-yr-old boy with a proximal skeletal myopathy and a cardiomyopathy, has shown a major increase in mitochondrial size and numbers on electron-microscopic morphometry, with formation of unique ring-shaped mitochondria in cardiac muscle cells. The significance of this finding and the use of cardiac biopsy in children are discussed.