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Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

✍ Scribed by Gross, Olaf; Gewies, Andreas; Finger, Katrin; Schäfer, Martin; Sparwasser, Tim; Peschel, Christian; Förster, Irmgard; Ruland, Jürgen


Book ID
109895999
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
581 KB
Volume
442
Category
Article
ISSN
0028-0836

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Card9 controls a non-TLR signalling path
✍ Gross, Olaf; Gewies, Andreas; Finger, Katrin; Schäfer, Martin; Sparwasser, Tim; 📂 Article 📅 2006 🏛 Nature Publishing Group 🌐 English ⚖ 581 KB

Fungal infections are increasing worldwide due to the marked rise in immunodeficiencies including AIDS; however, immune responses to fungi are poorly understood. Dectin-1 is the major mammalian pattern recognition receptor for the fungal component zymosan. Dectin-1 represents the prototype of innate