Carcinoma of the nasopharynx: Analysis of treatment results in 167 consecutively admitted patients

✍ Scribed by Dr. Lars Vendelbo Johansen; Miguel Mestre; Jens Overgaard

• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 528 KB
• Volume: 14
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.2880140307

✦ Synopsis

Radiotherapy with curative intent was administered to 159 of 167 consecutively admitted patients with nasophatyngeal carcinoma. The classification (UICC 1982) gave the staging: stage I 8%, stage II 2%, stage 111 28%, and stage IV 61%.

The actuarial local tumor control was 54% and correlated to the T-classification. Primary control of neck nodes was 67% but was not correlated to the N-classes. Distant failure occurred in 20% of the patients; this was correlated to the N-classification.

The 1 0-year actuarially corrected survival rate was 37% (stage 1+11 6O%, stage 111 49%, stage IV 27%). Late reactions were seen in 69%, and most patients had mild to moderate xerostomia. Men with high hemoglobin had a better prognosis than men with values in the lower part of the normal range. It is concluded that primary control in the T-and N-positions is the parameter most crucial to success.