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Carcinogenicity and metabolic profiles of 6-substituted benzo[a]pyrene derivatives on mouse skin

✍ Scribed by E. Cavalieri; R. Roth; C. Grandjean; J. Althoff; K. Patil; S. Liakus; S. Marsh

Book ID
113135978
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
861 KB
Volume
22
Category
Article
ISSN
0009-2797

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✍ James L. Hicks; J. Richard Heys πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 332 KB

## Abstract 6‐Lithiobenzo[__a__]pyrene was carbonated to produce benzo[__a__]pyrene‐6‐carboxylic‐^14^C acid, which was in turn used in the preparation of several derivatives. Methylation to the ester was followed by LiAlH~4~ reduction to 6‐hydroxymethyl‐^14^C‐benzo[__a__]pyrene. An efficient oxidat