✦ LIBER ✦

Carcinogenic Potency of N-Nitrosomethyl(2-hydroxypropyl)amine and Other Metabolic Relatives of N-Nitrosobis(2-hydroxypropyl)amine by Single Intraperitoneal Injection on the Lung of Rats

✍ Scribed by Yokose, Yoshihiko ;Yamamoto, Kazuhiko ;Nakajima, Akira ;Eimoto, Hiroyuki ;Maruyama, Hiroshi ;Mori, Yukio ;Konishi, Yoichi

Book ID: 108578763
Publisher: Wiley (Blackwell Publishing)
Year: 1988
Tongue: English
Weight: 346 KB
Volume: 79
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1988.tb02225.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hypermethylation of the Dal-1 gene in lu

Hypermethylation of the Dal-1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Toshifumi Tsujiuchi; Tomomi Masaoka; Eriko Sugata; Mariko Onishi; Hiromasa Fujii 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB

## Abstract DAL‐1 (differentially expressed in adenocarcinoma of the lung) is an actin‐binding protein that has been shown to suppress growth in lung cancer cells. Recently, inactivation of the gene encoding DAL‐1 due to hypermethylation has been found in several human malignancies, including lung

Alterations of the Dutt1/Robo1 gene in l

Alterations of the Dutt1/Robo1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Masahiro Tsuts 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 148 KB

## Abstract Abnormalities of tumor suppressor genes (TSGs) on chromosome 3p are known to be important for the development of human lung cancers. In the present study, we investigated alterations of the __Dutt1__/__Robo1__ gene, as a possible tumor suppressor in this region, in rat lung adenocarcino

Mutations of the Smad2 and Smad4 genes i

Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 1 views

Alterations of the M6p/Igf2 receptor gen

Alterations of the M6p/Igf2 receptor gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB

## Abstract Alterations of the mannose 6‐phosphate/insulin‐like growth factor II receptor (__M6p/lgf2r__) gene were investigated in lung adenocarcinomas induced by N‐nitrosobis(2‐hydroxypropyl)amine (BHP) in rats. Male Wistar rats, 6 wk old, were given 2000 ppm BHP in their drinking water for 12 wk

Reduced expressions of Foxp1 and Rassf1a

Reduced expressions of Foxp1 and Rassf1a genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Kyoko Shimizu; Ayumi Kato; Daisei Hinotsume; Mayumi Shigemura; Madoka Hanaoka; Y 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 141 KB

Expression of vascular endothelial growt

Expression of vascular endothelial growth factor and its receptors during lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Makoto Takahama; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Akira Kido; Hiroyuki Sa 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB 👁 1 views

The expression of vascular endothelial growth factor (VEGF) and its receptors (VEGFRs), VEGFR-1/Flt-1 and VEGFR-2/Flk-1, was investigated by immunohistochemical and northern blot analysis during lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine (BHP) in male Wistar rats. After BHP was given