๐”– Bobbio Scriptorium
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Carcinogenic Activity and O-Alkylation

โœ Scribed by SCHOENTAL, R.

Book ID
109600224
Publisher
Nature Publishing Group
Year
1958
Tongue
English
Weight
350 KB
Volume
182
Category
Article
ISSN
0028-0836

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## Abstract Methylation reactions of the DNA bases with the methane diazonium ion, which is the reactive intermediate formed from several carcinogenic methylating agents, were examined. The S~N~2 transition states of the methylation reactions at N7, N3, and O^6^ of guanine; N7, N3, and N1 of adenin