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Carcinogenesis studies of benzophenone in rats and mice

✍ Scribed by M.C. Rhodes; J.R. Bucher; J.C. Peckham; G.E. Kissling; M.R. Hejtmancik; R.S. Chhabra

Book ID: 116461799
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 162 KB
Volume: 45
Category: Article
ISSN: 0278-6915
DOI: 10.1016/j.fct.2006.11.003

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## Abstract Sprague‐Dawley rats and NMRI mice were treated with urethane in the drinking water for 2 years. In both species the daily doses were: 100, 500, 2,500, and 12,500 μg/kg. The frequency of animals with malignancies increased steadily with increasing doses, beginning from 500 μg/kg/day for