Carcinoembryonic antigen by radioimmunoassay in the detection of recurrence during long-term followup of female genital cancer
✍ Scribed by Dr. S. K. Khoo; Professor. E. V. Mackay
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 652 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
In the study, radioimmunoassay for carcinoembryonic antigen (CEA) was used in 75 patients with female genital cancer, who were followed u p on a longterm basis. These patients were assessed for the following disease status a t each visit: free of disease, residual disease, or recurrence of disease. They also had periodic determinations of CEA i n serum performed independently. The majority of patients who remained free of disease showed a rapid disappearance of CEA after treatment, whereas those who had residual disease continued to show persistence of CEA in serum. The patients who developed recurrence showed a re-appearance of CEA after its initial disappearance; the mean time interval between re-appearance of CEA and detection of clinical recurrence was 10.7 weeks. T h e CEA assay is considered to be a useful aid to the assessment of subsequent behavior of the tumor after primary treatment.