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Carboxyterminal cleavage of the chemokines MIG and IP-10 by gelatinase B and neutrophil collagenase

โœ Scribed by Philippe E Van den Steen; Steven J Husson; Paul Proost; Jo Van Damme; Ghislain Opdenakker


Book ID
116287162
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
416 KB
Volume
310
Category
Article
ISSN
0006-291X

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Integrin-mediated adhesion to the vascular endothelium is an essential step in leukocyte diapedesis. We show that the chemokines 10-kDa inflammatory protein (IP10) and monokine induced by IFN (Mig) induce rapid and transient adhesion of human IL-2-stimulated T lymphocytes (IL-2 T cells) to immobiliz