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Carboxyl-terminal structure of basic fibroblast growth factor significantly contributes to its affinity for heparin

โœ Scribed by Masaharu SENO; Reiko SASADA; Tsutomu KUROKAWA; Koichi IGARASHI


Book ID
115127743
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
682 KB
Volume
188
Category
Article
ISSN
1432-1327

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Acidic and basic fibroblast growth facto
โœ Kathryn J. Brown; Ian A. Hendry; Christopher R. Parish ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 806 KB

Heparan sulfate proteoglycans on the cell surface act as low affinity binding sites for acidic and basic fibroblast growth factor (FGF) [Moscatelli (1987): J Cell Physiol 131:123-1301 and play an important role in the interaction of FGF with the FGF receptor (FGFR). In this study, several aspects of